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ALPCO
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OriGene
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ALPCO
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Bachem
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Bachem
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NEN Life Science
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DuPont de Nemours
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Bachem
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Auspep Pty
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Bachem
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Image Search Results
Journal: Diabetologia
Article Title: Opposing roles of the entero-pancreatic hormone urocortin-3 in glucose metabolism in rats.
doi: 10.1007/s00125-022-05675-9
Figure Lengend Snippet: Fig. 5 Crhr2 expression in the rat gastrointestinal tract. Representative images of chromogenic in situ hybridisa- tion staining of Crhr2 mRNA (red) in interstitial cells of Cajal along the submucosal surface of the circular smooth muscle layer in the pyloric antrum and the small intestine (a), submucous plexus of the gastric corpus and pyloric antrum (b) and smooth muscle layer of arterioles in the gastric corpus, small and large intestine, pancreas, and mesentery (c). Nuclei were counterstained with haematoxy- lin. Scale bar, 20 μm (a, b) or 30 μm (c). n = 3 (male rats). Ms, muscularis propria; Mu, mucosa; S, submucosa
Article Snippet: Pharmacology studies COS-7 cells were modified for either mouse or rat CRHR2 expression using a transient calcium phosphate precipitation transfection procedure [9] with pCMV6-Entry vectors containing
Techniques: Expressing, In Situ, Staining
Journal: Frontiers in Neuroscience
Article Title: Corticotropin-Releasing Factor Receptors Modulate Oxytocin Release in the Dorsolateral Bed Nucleus of the Stria Terminalis (BNST) in Male Rats
doi: 10.3389/fnins.2018.00183
Figure Lengend Snippet: CRFR manipulation affects OT content in BNST dl microdialysates.
Article Snippet: CRFR2 agonist, Urocortin 3 (mouse) trifluroacetate (Ucn3) and
Techniques:
Journal: Frontiers in Neuroscience
Article Title: Corticotropin-Releasing Factor Receptors Modulate Oxytocin Release in the Dorsolateral Bed Nucleus of the Stria Terminalis (BNST) in Male Rats
doi: 10.3389/fnins.2018.00183
Figure Lengend Snippet: The effect of CRFR2 antagonist (As2B) on OT content in BNST dl microdialysates is modulated by CRFR1 manipulation. The effect of As2B on OT release at 30 min was occluded by intra-BNST dl application of CRFR1 antagonist NBI 35965 ( n = 6, teal, open circle, P < 0.05) as well as application of CRF ( n = 7, blue diamond, P < 0.01). The delayed stimulatory effect of As2B at 90 min was not affected by CRF or NBI 35965 application ( P > 0.05). ** P < 0.01, * P < 0.05, two-way ANOVA with repeated measures.
Article Snippet: CRFR2 agonist, Urocortin 3 (mouse) trifluroacetate (Ucn3) and
Techniques:
Journal: Frontiers in Neuroscience
Article Title: Corticotropin-Releasing Factor Receptors Modulate Oxytocin Release in the Dorsolateral Bed Nucleus of the Stria Terminalis (BNST) in Male Rats
doi: 10.3389/fnins.2018.00183
Figure Lengend Snippet: OT content in BNST dl microdialysates is modulated by CRF. CRF caused a significant increase in OT release at 90 min ( n = 9, red triangle, P < 0.001 in comparison to ACSF group). CRFR1 blockade by NBI 35965 did not significantly affect the effect of CRF on OT release ( n = 8, cyan, open square, P > 0.05). However, blocking CRFR2 with As2B abolished the effect of CRF on OT release ( n = 7, blue diamond, P < 0.01). *** P < 0.001, ** P < 0.01 two-way ANOVA with repeated measures.
Article Snippet: CRFR2 agonist, Urocortin 3 (mouse) trifluroacetate (Ucn3) and
Techniques: Comparison, Blocking Assay